Atrial Giant Cell Myocarditis : A Distinctive Clinicopathologic Entity Running title

Atrial Giant Cell Myocarditis: A Distinctive Clinicopathologic Entity Running title: Larsen et al.; Atrial giant cell myocarditis

Atrial giant cell myocarditis: a distinctive clinicopathologic entity.

BACKGROUND Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinical features and follows a more benign course than ventricular GCM. METHODS A...

When giant cell myocarditis affects only the atria.

I n this issue of Circulation, Larsen et al 1 report a new variant of giant cell myocarditis (GCM) with lone involvement of the atria and preserved left ventricular function. The diagnosis was supported not only by histology but also by cardiac magnetic resonance imaging showing atrial dilatation and wall thickening with marked edema, sparing the ventricles. The isolated atrial involvement was ...

Idiopathic giant cell myocarditis--a distinctive clinico-pathological entity.

Eleven cases of idiopathic giant cell myocarditis are described, The pathological features are unmistakable with serpiginous areas of myocardial necrosis, at the margins of which giant cells can be seen on histological examination. The aetiology of the condition remains obscure but associated pathology suggests that altered immunity may be a factor. The rapid clinical course is, however, highly...

Giant Cell Carcinoma of Endometrium: a Rare Clinical Entity

Giant cell carcinoma of the endometrium is a rare and an aggressive tumor that should be distinguished from other endometrial tumors with a prominent giant cell component, including trophoblastic tumors, certain primary sarcomas, and malignant mixed müllerian tumors. At present, cumulative data on this rare histological variant is limited and the prognostic significance of the presence and the ...